Clinical Review: Congenital Hypertrophy of the Retinal Pigment Epithelium (CHRPE)

CHRPE represents RPE cells that are twice their normal size and contain densely packed, large melanin granules. CHRPE lesions tend to be unilateral in most cases and can be located anywhere in the retina, primarily temporally or in the periphery. Their diameter varies from approximately 2 to 6 mm, and most commonly appear jet black …

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