October 7, 2011 | POSTED BY | Clinical Pearls

Know your pharmacology including similarities between different classes of drugs. You will want to avoid using cephalosporins such as Keflex in a patient with reported allergies to penicillins. There is a well known cross allergenicity between the two classes of drugs, so it may be best in some circumstances to avoid using both classes of drugs in the event a penicillin allergy is reported in case history.

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